The National HIV/AIDS Secretariat was established by an act of Parliament in 2002 and located in the Office of the President to coordinate a multi-sectoral effort to reduce the spread of HIV/AIDS and mitigate its impact in Sierra Leone.

The National HIV/AIDS Secretariat is committed to providing leadership in coordination of HIV/AIDS programs and activities of all stakeholders in Sierra Leone by developing, implementing and coordinating an effective strategic plan that addresses prevention, treatment, care and assures the preservation of human right.

The mission is translated into the following functional areas:

• Guide policy formulation and establishment of programme priorities
• Take the lead in national planning and monitoring
• Spearhead advocacy for HIV/AIDS activities
• Identify and address obstacles to the national response
• Mobilize and monitor resources allocation and utilization
• Foster linkages among partners
• Provide guidelines and technical assistance for implementation
• Gather ands disseminate information
• Promote HIV/AIDS related research