The secretariat is currently headed by a Director, Dr. Brima Kargbo, who also serves as secretary to the National AIDS Council (NAC). His Excellency the President of the Republic of Sierra Leone, Dr Ernest Bai Koroma, is the Chairman of NAC.
The Director is assisted by the following professional staff:

• Deputy Director
  
• Team Leader, National AIDS Control Programme (NACP)
• Admin and Finance Coordinator
• Capacity Building and Training Specialist
• Information, Education and Communication/Behavioural Change Communication Specialist
• Monitoring and Evaluation Specialist
• Procurement Specialist (KPMG)
• Financial Specialist (KPMG)
• Health Administrator, National AIDS Control Programme (NACP)
• Documentation Officer
• Information Technology Manager

Procurement and financial management is provided by a financial Management firm- KPMG. The financial management system includes accounting, project management and procurement reporting, and auditing elements.